humantemplate

Lactobacillus F19 has been shown to be an effective probiotic culture. It can survive the upper GI tract, which is not surprising considering F19 can grow in the presence of human bile. MRS media was supplemented with 0.3, 0.5, and 5.0 % human bile and was inoculated with Lactobacillus F19 (Figure 8). F19 grew in all concentrations of bile tested. In another experiment, F19 even survived for 2 hours in MRS broth with 20% ox gall added. It also has been shown that F19 grows in the presence of bile without deconjugating bile salts.

In addition, Ljungh et al (2002) showed that F19 could survive in lower pH ranges. Lactobacillus F19 was added to MRS broth adjusted to a pH of 2.5 using 1 M HCl. F19 survived for one hour when incubated at 30^oC (86^oF). Figure 8. Fecal counts of Lactobacillus F19
in elderly treatment participants.

Knowing that the adverse environment of the stomach was no obstacle for
Lactobacillus F19, Ljungh et al also testing the binding affinities of the culture.
It was determined that F19 had a high surface hydrophobicity. It has excellent
adhesion to mucin, collagens I and III, fibrinogen, heparin, and fibronectin.
Kapczynski et al (2000) correlated fibronectin binding ability to adherence